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The Role of Cystinosin in the Intermediary Thiol Metabolism and Redox Homeostasis in Kidney Proximal Tubular Cells

Cystinosin is a lysosomal transmembrane protein which facilitates transport of the disulphide amino acid cystine (CySS) from the lysosomes of the cell. This protein is encoded by the CTNS gene which is defective in the lysosomal storage disorder, cystinosis. Because of the apparent involvement of cy...

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Detalles Bibliográficos
Autores principales: Sumayao, Rodolfo, Newsholme, Philip, McMorrow, Tara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315507/
https://www.ncbi.nlm.nih.gov/pubmed/30513914
http://dx.doi.org/10.3390/antiox7120179