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A Systematic Overview of Type II and III Toxin-Antitoxin Systems with a Focus on Druggability

Toxin-antitoxin (TA) systems are known to play various roles in physiological processes, such as gene regulation, growth arrest and survival, in bacteria exposed to environmental stress. Type II TA systems comprise natural complexes consisting of protein toxins and antitoxins. Each toxin and antitox...

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Detalles Bibliográficos
Autores principales: Kang, Sung-Min, Kim, Do-Hee, Jin, Chenglong, Lee, Bong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315513/
https://www.ncbi.nlm.nih.gov/pubmed/30518070
http://dx.doi.org/10.3390/toxins10120515