Human Recombinant Fab Fragment Neutralizes Shiga Toxin Type 2 Cytotoxic Effects in vitro and in vivo

Shiga toxin (Stx) producing Escherichia coli (STEC) is responsible for causing hemolytic uremic syndrome (HUS), a life-threatening thrombotic microangiopathy characterized by thrombocytopenia, hemolytic anemia, and acute renal failure after bacterially induced hemorrhagic diarrhea. Until now, there...

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Detalles Bibliográficos
Autores principales: Luz, Daniela, Amaral, Maria Marta, Sacerdoti, Flavia, Bernal, Alan Mauro, Quintilio, Wagner, Moro, Ana Maria, Palermo, Marina Sandra, Ibarra, Cristina, Piazza, Roxane Maria Fontes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315604/
https://www.ncbi.nlm.nih.gov/pubmed/30513821
http://dx.doi.org/10.3390/toxins10120508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315604/
https://www.ncbi.nlm.nih.gov/pubmed/30513821
http://dx.doi.org/10.3390/toxins10120508

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