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Enhancing the Anticancer Efficacy of Immunotherapy through Combination with Histone Modification Inhibitors
In the nucleus of each cell, the DNA is wrapped around histone octamers, forming the so-called “nucleosomal core particles”. The histones undergo various modifications that influence chromatin structure and function, including methylation, acetylation, ubiquitination, phosphorylation, and SUMOylatio...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315613/ https://www.ncbi.nlm.nih.gov/pubmed/30558227 http://dx.doi.org/10.3390/genes9120633 |