Repetitive Fragile Sites: Centromere Satellite DNA as a Source of Genome Instability in Human Diseases

Maintenance of an intact genome is essential for cellular and organismal homeostasis. The centromere is a specialized chromosomal locus required for faithful genome inheritance at each round of cell division. Human centromeres are composed of large tandem arrays of repetitive alpha-satellite DNA, wh...

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Detalles Bibliográficos
Autores principales: Black, Elizabeth M., Giunta, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315641/
https://www.ncbi.nlm.nih.gov/pubmed/30544645
http://dx.doi.org/10.3390/genes9120615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315641/
https://www.ncbi.nlm.nih.gov/pubmed/30544645
http://dx.doi.org/10.3390/genes9120615

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