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Repetitive Fragile Sites: Centromere Satellite DNA as a Source of Genome Instability in Human Diseases
Maintenance of an intact genome is essential for cellular and organismal homeostasis. The centromere is a specialized chromosomal locus required for faithful genome inheritance at each round of cell division. Human centromeres are composed of large tandem arrays of repetitive alpha-satellite DNA, wh...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315641/ https://www.ncbi.nlm.nih.gov/pubmed/30544645 http://dx.doi.org/10.3390/genes9120615 |