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A Pilot Study to Non-Invasively Track PIK3CA Mutation in Head and Neck Cancer

Background: PIK3CA pathways are the most frequently mutated oncogenic pathway in head and neck squamous cell carcinoma (HNSCC), including virally driven HNCs. PIK3CA is involved in the PI3K-PTEN-mTOR signalling pathway. PIK3CA has been implicated in HNSCC progression and PIK3CA mutations may serve a...

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Detalles Bibliográficos
Autores principales: Schmidt, Henri, Kulasinghe, Arutha, Allcock, Richard J.N., Tan, Lit Yeen, Mokany, Elisa, Kenny, Liz, Punyadeera, Chamindie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315660/
https://www.ncbi.nlm.nih.gov/pubmed/30501041
http://dx.doi.org/10.3390/diagnostics8040079