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The Disruption of the β-Catenin/TCF-1/STAT3 Signaling Axis by 4-Acetylantroquinonol B Inhibits the Tumorigenesis and Cancer Stem-Cell-Like Properties of Glioblastoma Cells, In Vitro and In Vivo

Background: Glioblastoma (GBM), a malignant form of glioma, is characterized by resistance to therapy and poor prognosis. Accumulating evidence shows that the initiation, propagation, and recurrence of GBM is attributable to the presence of GBM stem cells (GBM-CSCs). Experimental approach: Herein, w...

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Detalles Bibliográficos
Autores principales: Liu, Heng-Wei, Su, Yu-Kai, Bamodu, Oluwaseun Adebayo, Hueng, Dueng-Yuan, Lee, Wei-Hwa, Huang, Chun-Chih, Deng, Li, Hsiao, Michael, Chien, Ming-Hsien, Yeh, Chi-Tai, Lin, Chien-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315804/
https://www.ncbi.nlm.nih.gov/pubmed/30563094
http://dx.doi.org/10.3390/cancers10120491