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IL-12 Gene Electrotransfer Triggers a Change in Immune Response within Mouse Tumors

Metastatic melanoma is an aggressive skin cancer with a relatively low survival rate. Immune-based therapies have shown promise in the treatment of melanoma, but overall complete response rates are still low. Previous studies have demonstrated the potential of plasmid IL-12 (pIL-12) delivered by gen...

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Detalles Bibliográficos
Autores principales: Shi, Guilan, Edelblute, Chelsea, Arpag, Sezgi, Lundberg, Cathryn, Heller, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315808/
https://www.ncbi.nlm.nih.gov/pubmed/30544810
http://dx.doi.org/10.3390/cancers10120498