Common Chromosomal Fragile Sites—Conserved Failure Stories

In order to pass on an intact copy of the genome during cell division, complete and faithful DNA replication is crucial. Yet, certain areas of the genome are intrinsically challenging to replicate, which manifests as high local mutation propensity. Such regions include trinucleotide repeat sequences...

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Detalles Bibliográficos
Autores principales: Voutsinos, Vasileios, Munk, Sebastian H. N., Oestergaard, Vibe H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315858/
https://www.ncbi.nlm.nih.gov/pubmed/30486458
http://dx.doi.org/10.3390/genes9120580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315858/
https://www.ncbi.nlm.nih.gov/pubmed/30486458
http://dx.doi.org/10.3390/genes9120580

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