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mTOR Activation in Liver Tumors Is Associated with Metabolic Syndrome and Non-Alcoholic Steatohepatitis in Both Mouse Models and Humans

Non-alcoholic steatohepatitis (NASH) can cause liver fibrosis and cirrhosis, with final progression to hepatocellular carcinoma (HCC) in some cases. Various factors have been suggested to be involved in the development of NASH. Considering the many possible contributing factors, we postulated that m...

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Detalles Bibliográficos
Autores principales: Okuno, Takahiro, Kakehashi, Anna, Ishii, Naomi, Fujioka, Masaki, Gi, Min, Wanibuchi, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315895/
https://www.ncbi.nlm.nih.gov/pubmed/30469530
http://dx.doi.org/10.3390/cancers10120465