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mTOR Activation in Liver Tumors Is Associated with Metabolic Syndrome and Non-Alcoholic Steatohepatitis in Both Mouse Models and Humans
Non-alcoholic steatohepatitis (NASH) can cause liver fibrosis and cirrhosis, with final progression to hepatocellular carcinoma (HCC) in some cases. Various factors have been suggested to be involved in the development of NASH. Considering the many possible contributing factors, we postulated that m...
Autores principales: | Okuno, Takahiro, Kakehashi, Anna, Ishii, Naomi, Fujioka, Masaki, Gi, Min, Wanibuchi, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315895/ https://www.ncbi.nlm.nih.gov/pubmed/30469530 http://dx.doi.org/10.3390/cancers10120465 |
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