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GSK461364A, a Polo-Like Kinase-1 Inhibitor Encapsulated in Polymeric Nanoparticles for the Treatment of Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme (GBM) is a common primary brain cancer with a poor prognosis and a median survival of less than 14 months. Current modes of treatment are associated with deleterious side effects that reduce the life span of the patients. Nanomedicine enables site-specific delivery of active...

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Detalles Bibliográficos
Autores principales: Velpurisiva, Praveena, Piel, Brandon P., Lepine, Jack, Rai, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315921/
https://www.ncbi.nlm.nih.gov/pubmed/30304810
http://dx.doi.org/10.3390/bioengineering5040083