Cargando…
GSK461364A, a Polo-Like Kinase-1 Inhibitor Encapsulated in Polymeric Nanoparticles for the Treatment of Glioblastoma Multiforme (GBM)
Glioblastoma Multiforme (GBM) is a common primary brain cancer with a poor prognosis and a median survival of less than 14 months. Current modes of treatment are associated with deleterious side effects that reduce the life span of the patients. Nanomedicine enables site-specific delivery of active...
Autores principales: | Velpurisiva, Praveena, Piel, Brandon P., Lepine, Jack, Rai, Prakash |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315921/ https://www.ncbi.nlm.nih.gov/pubmed/30304810 http://dx.doi.org/10.3390/bioengineering5040083 |
Ejemplares similares
-
Synergistic Action of Gefitinib and GSK41364A Simultaneously Loaded in Ratiometrically-Engineered Polymeric Nanoparticles for Glioblastoma Multiforme
por: Velpurisiva, Praveena, et al.
Publicado: (2019) -
The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models
por: Pajtler, Kristian W, et al.
Publicado: (2016) -
Using Light for Therapy of Glioblastoma Multiforme (GBM)
por: Vasilev, Alex, et al.
Publicado: (2020) -
FAM72, Glioblastoma Multiforme (GBM) and Beyond
por: Ho, Nguyen Thi Thanh, et al.
Publicado: (2021) -
Unusually High Affinity of the PLK Inhibitors RO3280
and GSK461364 to HSA and Its Possible Pharmacokinetic Implications
por: Fernández-Sainz, Jesús, et al.
Publicado: (2023)