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Gastric Stem Cell and Cellular Origin of Cancer

Several stem cell markers within the gastrointestinal epithelium have been identified in mice. One of the best characterized is Lgr5 (leucine-rich repeat-containing G-protein coupled receptor 5) and evidence suggests that Lgr5+ cells in the gut are the origin of gastrointestinal cancers. Reserve or...

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Detalles Bibliográficos
Autores principales: Hata, Masahiro, Hayakawa, Yoku, Koike, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315982/
https://www.ncbi.nlm.nih.gov/pubmed/30384487
http://dx.doi.org/10.3390/biomedicines6040100