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Peripheral Anti-Angiogenic Imbalance during Pregnancy Impairs Myogenic Tone and Increases Cerebral Edema in a Rodent Model of HELLP Syndrome

Using an animal model of hemolysis elevated liver enzymes low platelets (HELLP) that has systemic inflammation and neuroinflammation we wanted to determine if blood brain barrier (BBB) permeability, cerebral edema, vascular tone, and occludin expression were altered in pregnant rats. Anti-angiogenic...

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Detalles Bibliográficos
Autores principales: Bean, Cynthia, Spencer, Shauna-Kay, Pabbidi, Mallikarjuna R., Szczepanski, Jamie, Araji, Sarah, Dixon, Sellena, Wallace, Kedra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316026/
https://www.ncbi.nlm.nih.gov/pubmed/30563221
http://dx.doi.org/10.3390/brainsci8120216