Rapid, Reproducible, Quantifiable NMR Metabolomics: Methanol and Methanol: Chloroform Precipitation for Removal of Macromolecules in Serum and Whole Blood

Background: Though blood is an excellent biofluid for metabolomics, proteins and lipids present in blood can interfere with 1d-(1)H NMR spectra and disrupt quantification of metabolites. Here, we present effective macromolecule removal strategies for serum and whole blood (WB) samples. Methods: A va...

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Detalles Bibliográficos
Autores principales: McHugh, Cora E., Flott, Thomas L., Schooff, Casey R., Smiley, Zyad, Puskarich, Michael A., Myers, Daniel D., Younger, John G., Jones, Alan E., Stringer, Kathleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316042/
https://www.ncbi.nlm.nih.gov/pubmed/30558115
http://dx.doi.org/10.3390/metabo8040093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316042/
https://www.ncbi.nlm.nih.gov/pubmed/30558115
http://dx.doi.org/10.3390/metabo8040093

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