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Sex Differences in Context-Driven Reinstatement of Methamphetamine Seeking is Associated with Distinct Neuroadaptations in the Dentate Gyrus

The present study examined differences in operant responses in adult male and female rats during distinct phases of addiction. Males and females demonstrated escalation in methamphetamine (0.05 mg/kg, i.v.) intake with females showing enhanced latency to escalate, and bingeing. Following protracted...

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Detalles Bibliográficos
Autores principales: Takashima, Yoshio, Tseng, Joyee, Fannon, McKenzie J., Purohit, Dvijen C., Quach, Leon W., Terranova, Michael J., Kharidia, Khush M., Oliver, Robert J., Mandyam, Chitra D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316047/
https://www.ncbi.nlm.nih.gov/pubmed/30487415
http://dx.doi.org/10.3390/brainsci8120208