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Sex Differences in Context-Driven Reinstatement of Methamphetamine Seeking is Associated with Distinct Neuroadaptations in the Dentate Gyrus
The present study examined differences in operant responses in adult male and female rats during distinct phases of addiction. Males and females demonstrated escalation in methamphetamine (0.05 mg/kg, i.v.) intake with females showing enhanced latency to escalate, and bingeing. Following protracted...
Autores principales: | Takashima, Yoshio, Tseng, Joyee, Fannon, McKenzie J., Purohit, Dvijen C., Quach, Leon W., Terranova, Michael J., Kharidia, Khush M., Oliver, Robert J., Mandyam, Chitra D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316047/ https://www.ncbi.nlm.nih.gov/pubmed/30487415 http://dx.doi.org/10.3390/brainsci8120208 |
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