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Fucoidan-Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Co-Targeting Tumor Hypoxia and Angiogenesis

Tumor hypoxia is a major mechanism of resistance to radiation therapy (RT), which is associated with poor prognosis in affected cancer patients. Various approaches to treat hypoxic and radioresistant cancers, including pancreatic cancer, have shown limited success. Fucoidan, a polysaccharide from br...

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Detalles Bibliográficos
Autores principales: Shin, Sung-Won, Jung, Wooju, Choi, Changhoon, Kim, Shin-Yeong, Son, Arang, Kim, Hakyoung, Lee, Nohyun, Park, Hee Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316049/
https://www.ncbi.nlm.nih.gov/pubmed/30558324
http://dx.doi.org/10.3390/md16120510