Cyclooxygenase-1 (COX-1) and COX-1 Inhibitors in Cancer: A Review of Oncology and Medicinal Chemistry Literature

Prostaglandins and thromboxane are lipid signaling molecules deriving from arachidonic acid by the action of the cyclooxygenase isoenzymes COX-1 and COX-2. The role of cyclooxygenases (particularly COX-2) and prostaglandins (particularly PGE(2)) in cancer-related inflammation has been extensively in...

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Detalles Bibliográficos
Autores principales: Pannunzio, Alessandra, Coluccia, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316056/
https://www.ncbi.nlm.nih.gov/pubmed/30314310
http://dx.doi.org/10.3390/ph11040101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316056/
https://www.ncbi.nlm.nih.gov/pubmed/30314310
http://dx.doi.org/10.3390/ph11040101

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