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Cyclooxygenase-1 (COX-1) and COX-1 Inhibitors in Cancer: A Review of Oncology and Medicinal Chemistry Literature

Prostaglandins and thromboxane are lipid signaling molecules deriving from arachidonic acid by the action of the cyclooxygenase isoenzymes COX-1 and COX-2. The role of cyclooxygenases (particularly COX-2) and prostaglandins (particularly PGE(2)) in cancer-related inflammation has been extensively in...

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Detalles Bibliográficos
Autores principales:	Pannunzio, Alessandra, Coluccia, Mauro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316056/ https://www.ncbi.nlm.nih.gov/pubmed/30314310 http://dx.doi.org/10.3390/ph11040101

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