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Clogging the Ubiquitin-Proteasome Machinery with Marine Natural Products: Last Decade Update
The ubiquitin-proteasome pathway (UPP) is the central protein degradation system in eukaryotic cells, playing a key role in homeostasis maintenance, through proteolysis of regulatory and misfolded (potentially harmful) proteins. As cancer cells produce proteins inducing cell proliferation and inhibi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316072/ https://www.ncbi.nlm.nih.gov/pubmed/30486251 http://dx.doi.org/10.3390/md16120467 |