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Clogging the Ubiquitin-Proteasome Machinery with Marine Natural Products: Last Decade Update

The ubiquitin-proteasome pathway (UPP) is the central protein degradation system in eukaryotic cells, playing a key role in homeostasis maintenance, through proteolysis of regulatory and misfolded (potentially harmful) proteins. As cancer cells produce proteins inducing cell proliferation and inhibi...

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Detalles Bibliográficos
Autores principales: Della Sala, Gerardo, Agriesti, Francesca, Mazzoccoli, Carmela, Tataranni, Tiziana, Costantino, Valeria, Piccoli, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316072/
https://www.ncbi.nlm.nih.gov/pubmed/30486251
http://dx.doi.org/10.3390/md16120467