BRCA1-Dependent Transcriptional Regulation: Implication in Tissue-Specific Tumor Suppression

Germ-line mutations in breast cancer susceptibility gene 1 (BRCA1) predominantly predispose women to breast and ovarian cancers. BRCA1 is best known for its functions in maintenance of genomic integrity including repairing DNA double-strand breaks through homologous recombination and suppressing DNA...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaowen, Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316118/
https://www.ncbi.nlm.nih.gov/pubmed/30558184
http://dx.doi.org/10.3390/cancers10120513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316118/
https://www.ncbi.nlm.nih.gov/pubmed/30558184
http://dx.doi.org/10.3390/cancers10120513

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