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BRCA1-Dependent Transcriptional Regulation: Implication in Tissue-Specific Tumor Suppression
Germ-line mutations in breast cancer susceptibility gene 1 (BRCA1) predominantly predispose women to breast and ovarian cancers. BRCA1 is best known for its functions in maintenance of genomic integrity including repairing DNA double-strand breaks through homologous recombination and suppressing DNA...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316118/ https://www.ncbi.nlm.nih.gov/pubmed/30558184 http://dx.doi.org/10.3390/cancers10120513 |