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Selective Pressures on Human Cancer Genes along the Evolution of Mammals

Cancer is a disease driven by both somatic mutations that increase survival and proliferation of cell lineages and the evolution of genes associated with cancer risk in populations. Several genes associated with cancer in humans, hereafter cancer genes, show evidence of germline positive selection a...

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Detalles Bibliográficos
Autores principales: Vicens, Alberto, Posada, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316132/
https://www.ncbi.nlm.nih.gov/pubmed/30487452
http://dx.doi.org/10.3390/genes9120582