SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock

The role of stress-induced increases in SUMO2/3 conjugation during the heat shock response (HSR) has remained enigmatic. We investigated SUMO signal transduction at the proteomic and functional level during the HSR in cells depleted of proteostasis network components via chronic heat shock factor 1...

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Detalles Bibliográficos
Autores principales: Liebelt, Frauke, Sebastian, Rebecca M., Moore, Christopher L., Mulder, Monique P.C., Ovaa, Huib, Shoulders, Matthew D., Vertegaal, Alfred C.O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316133/
https://www.ncbi.nlm.nih.gov/pubmed/30605679
http://dx.doi.org/10.1016/j.celrep.2018.12.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316133/
https://www.ncbi.nlm.nih.gov/pubmed/30605679
http://dx.doi.org/10.1016/j.celrep.2018.12.027

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