Cargando…

Probing the Occurrence of Soluble Oligomers through Amyloid Aggregation Scaling Laws

Drug discovery frequently relies on the kinetic analysis of physicochemical reactions that are at the origin of the disease state. Amyloid fibril formation has been extensively investigated in relation to prevalent and rare neurodegenerative diseases, but thus far no therapeutic solution has directl...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva, Alexandra, Sárkány, Zsuzsa, Fraga, Joana S., Taboada, Pablo, Macedo-Ribeiro, Sandra, Martins, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316134/
https://www.ncbi.nlm.nih.gov/pubmed/30287796
http://dx.doi.org/10.3390/biom8040108