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Probing the Occurrence of Soluble Oligomers through Amyloid Aggregation Scaling Laws
Drug discovery frequently relies on the kinetic analysis of physicochemical reactions that are at the origin of the disease state. Amyloid fibril formation has been extensively investigated in relation to prevalent and rare neurodegenerative diseases, but thus far no therapeutic solution has directl...
Autores principales: | Silva, Alexandra, Sárkány, Zsuzsa, Fraga, Joana S., Taboada, Pablo, Macedo-Ribeiro, Sandra, Martins, Pedro M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316134/ https://www.ncbi.nlm.nih.gov/pubmed/30287796 http://dx.doi.org/10.3390/biom8040108 |
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