Cargando…
A common molecular logic determines embryonic stem cell self‐renewal and reprogramming
During differentiation and reprogramming, new cell identities are generated by reconfiguration of gene regulatory networks. Here, we combined automated formal reasoning with experimentation to expose the logic of network activation during induction of naïve pluripotency. We find that a Boolean netwo...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316172/ https://www.ncbi.nlm.nih.gov/pubmed/30482756 http://dx.doi.org/10.15252/embj.2018100003 |