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Synergistic AML Cell Death Induction by Marine Cytotoxin (+)-1(R), 6(S), 1’(R), 6’(S), 11(R), 17(S)-Fistularin-3 and Bcl-2 Inhibitor Venetoclax

Treatment of acute myeloid leukemia (AML) patients is still hindered by resistance and relapse, resulting in an overall poor survival rate. Recently, combining specific B-cell lymphoma (Bcl)-2 inhibitors with compounds downregulating myeloid cell leukemia (Mcl)-1 has been proposed as a new effective...

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Detalles Bibliográficos
Autores principales: Florean, Cristina, Kim, Kyung Rok, Schnekenburger, Michael, Kim, Hyun-Jung, Moriou, Céline, Debitus, Cécile, Dicato, Mario, Al-Mourabit, Ali, Han, Byung Woo, Diederich, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316187/
https://www.ncbi.nlm.nih.gov/pubmed/30572618
http://dx.doi.org/10.3390/md16120518