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Synergistic AML Cell Death Induction by Marine Cytotoxin (+)-1(R), 6(S), 1’(R), 6’(S), 11(R), 17(S)-Fistularin-3 and Bcl-2 Inhibitor Venetoclax
Treatment of acute myeloid leukemia (AML) patients is still hindered by resistance and relapse, resulting in an overall poor survival rate. Recently, combining specific B-cell lymphoma (Bcl)-2 inhibitors with compounds downregulating myeloid cell leukemia (Mcl)-1 has been proposed as a new effective...
Autores principales: | Florean, Cristina, Kim, Kyung Rok, Schnekenburger, Michael, Kim, Hyun-Jung, Moriou, Céline, Debitus, Cécile, Dicato, Mario, Al-Mourabit, Ali, Han, Byung Woo, Diederich, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316187/ https://www.ncbi.nlm.nih.gov/pubmed/30572618 http://dx.doi.org/10.3390/md16120518 |
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