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High-Frequency Microdomain Ca(2+) Transients and Waves during Early Myelin Internode Remodeling

Ensheathment of axons by myelin is a highly complex and multi-cellular process. Cytosolic calcium (Ca(2+)) changes in the myelin sheath have been implicated in myelin synthesis, but the source of this Ca(2+) and the role of neuronal activity is not well understood. Using one-photon Ca(2+) imaging, w...

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Detalles Bibliográficos
Autores principales: Battefeld, Arne, Popovic, Marko A., de Vries, Sharon I., Kole, Maarten H.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316190/
https://www.ncbi.nlm.nih.gov/pubmed/30605675
http://dx.doi.org/10.1016/j.celrep.2018.12.039