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Back to the Future? The Fallopian Tube, Precursor Escape and a Dualistic Model of High-Grade Serous Carcinogenesis

Beginning with the discovery of the BRCA-associated ovarian cancer susceptibility genes and subsequent detailed examination of risk-reducing salpingo-oophorectomy (RRSO) specimens, a new paradigm of ovarian carcinogenesis has unfolded with attention to the distal fallopian tube. The primary focus ha...

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Detalles Bibliográficos
Autores principales: Soong, T. Rinda, Kolin, David L., Teschan, Nathan J., Crum, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316244/
https://www.ncbi.nlm.nih.gov/pubmed/30486509
http://dx.doi.org/10.3390/cancers10120468