Pharmacological Targeting of Pore-Forming Toxins as Adjunctive Therapy for Invasive Bacterial Infection

For many of the most important human bacterial infections, invasive disease severity is fueled by the cell damaging and pro-inflammatory effects of secreted pore-forming toxins (PFTs). Isogenic PFT-knockout mutants, e.g., Staphylococcus aureus lacking α-toxin or Streptococcus pneumoniae deficient in...

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Detalles Bibliográficos
Autores principales: Escajadillo, Tamara, Nizet, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316385/
https://www.ncbi.nlm.nih.gov/pubmed/30562923
http://dx.doi.org/10.3390/toxins10120542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316385/
https://www.ncbi.nlm.nih.gov/pubmed/30562923
http://dx.doi.org/10.3390/toxins10120542

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