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A Mechanism Underlying Attenuation of Recombinant Influenza A Viruses Carrying Reporter Genes

Influenza A viruses (IAV) carrying reporter genes provide a powerful tool to study viral infection and pathogenesis in vivo, however, incorporating a non-essential gene into the IAV genome often results in virus attenuation and genetic instability. Very few studies have systematically compared diffe...

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Detalles Bibliográficos
Autores principales: Zhao, Xiujuan, Wang, Lin, Cui, Qinghua, Li, Ping, Wang, Yanyan, Zhang, Yingying, Yang, Yong, Rong, Lijun, Du, Ruikun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316390/
https://www.ncbi.nlm.nih.gov/pubmed/30513620
http://dx.doi.org/10.3390/v10120679