The N-Terminus of the HIV-1 p6 Gag Protein Regulates Susceptibility to Degradation by IDE

As part of the Pr55(Gag) polyprotein, p6 fulfills an essential role in the late steps of the replication cycle. However, almost nothing is known about the functions of the mature HIV-1 p6 protein. Recently, we showed that p6 is a bona fide substrate of the insulin-degrading enzyme (IDE), a ubiquitou...

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Detalles Bibliográficos
Autores principales: Schmalen, Adrian, Karius-Fischer, Julia, Rauch, Pia, Setz, Christian, Korn, Klaus, Henklein, Petra, Fossen, Torgils, Schubert, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316412/
https://www.ncbi.nlm.nih.gov/pubmed/30545091
http://dx.doi.org/10.3390/v10120710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316412/
https://www.ncbi.nlm.nih.gov/pubmed/30545091
http://dx.doi.org/10.3390/v10120710

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