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The N-Terminus of the HIV-1 p6 Gag Protein Regulates Susceptibility to Degradation by IDE
As part of the Pr55(Gag) polyprotein, p6 fulfills an essential role in the late steps of the replication cycle. However, almost nothing is known about the functions of the mature HIV-1 p6 protein. Recently, we showed that p6 is a bona fide substrate of the insulin-degrading enzyme (IDE), a ubiquitou...
Autores principales: | Schmalen, Adrian, Karius-Fischer, Julia, Rauch, Pia, Setz, Christian, Korn, Klaus, Henklein, Petra, Fossen, Torgils, Schubert, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316412/ https://www.ncbi.nlm.nih.gov/pubmed/30545091 http://dx.doi.org/10.3390/v10120710 |
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