Cargando…

Perturbations in Traffic: Aberrant Nucleocytoplasmic Transport at the Heart of Neurodegeneration

Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Huntington’s disease (HD), are characterized by intracellular aggregation of proteins. In the case of ALS and FTD, these protein aggregates are found in the cytoplasm of affected neurons and c...

Descripción completa

Detalles Bibliográficos
Autores principales: Fahrenkrog, Birthe, Harel, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316434/
https://www.ncbi.nlm.nih.gov/pubmed/30486313
http://dx.doi.org/10.3390/cells7120232