Design of Linear and Cyclic Mutant Analogues of Dirucotide Peptide (MBP(82–98)) against Multiple Sclerosis: Conformational and Binding Studies to MHC Class II

Background: Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system. MS is a T cell-mediated disease characterized by the proliferation, infiltration, and attack of the myelin sheath by immune cells. Previous studies have shown that cyclization provides molecules with strict...

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Detalles Bibliográficos
Autores principales: Deraos, George, Kritsi, Eftichia, Matsoukas, Minos-Timotheos, Christopoulou, Konstantina, Kalbacher, Hubert, Zoumpoulakis, Panagiotis, Apostolopoulos, Vasso, Matsoukas, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316436/
https://www.ncbi.nlm.nih.gov/pubmed/30518150
http://dx.doi.org/10.3390/brainsci8120213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316436/
https://www.ncbi.nlm.nih.gov/pubmed/30518150
http://dx.doi.org/10.3390/brainsci8120213

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