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Combination of Roll Grinding and High-Pressure Homogenization Can Prepare Stable Bicelles for Drug Delivery

To improve the solubility of the drug nifedipine (NI), NI-encapsulated lipid-based nanoparticles (NI-LNs) have been prepared from neutral hydrogenated soybean phosphatidylcholine and negatively charged dipalmitoylphosphatidylglycerol at a molar ratio of 5/1 using by roll grinding and high-pressure h...

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Detalles Bibliográficos
Autores principales: Matsuo, Seira, Higashi, Kenjirou, Moribe, Kunikazu, Kimura, Shin-ichiro, Itai, Shigeru, Kondo, Hiromu, Iwao, Yasunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316440/
https://www.ncbi.nlm.nih.gov/pubmed/30513913
http://dx.doi.org/10.3390/nano8120998