Simultaneous Detection of Different Zika Virus Lineages via Molecular Computation in a Point-of-Care Assay

We have developed a generalizable “smart molecular diagnostic” capable of accurate point-of-care (POC) detection of variable nucleic acid targets. Our isothermal assay relies on multiplex execution of four loop-mediated isothermal amplification reactions, with primers that are degenerate and redunda...

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Detalles Bibliográficos
Autores principales: Bhadra, Sanchita, Saldaña, Miguel A., Han, Hannah Grace, Hughes, Grant L., Ellington, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316447/
https://www.ncbi.nlm.nih.gov/pubmed/30558136
http://dx.doi.org/10.3390/v10120714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316447/
https://www.ncbi.nlm.nih.gov/pubmed/30558136
http://dx.doi.org/10.3390/v10120714

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