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Simultaneous Detection of Different Zika Virus Lineages via Molecular Computation in a Point-of-Care Assay
We have developed a generalizable “smart molecular diagnostic” capable of accurate point-of-care (POC) detection of variable nucleic acid targets. Our isothermal assay relies on multiplex execution of four loop-mediated isothermal amplification reactions, with primers that are degenerate and redunda...
Autores principales: | Bhadra, Sanchita, Saldaña, Miguel A., Han, Hannah Grace, Hughes, Grant L., Ellington, Andrew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316447/ https://www.ncbi.nlm.nih.gov/pubmed/30558136 http://dx.doi.org/10.3390/v10120714 |
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