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T = 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display

The HIV-1 mature capsid (CA) assumes an amorphous, fullerene conical configuration due to its high flexibility. How native CA self-assembles is still unclear despite having well-defined structures of its pentamer and hexamer building blocks. Here we explored the self-assembly of an engineered capsid...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiqing, He, Maozhou, Bai, Shimeng, Zhang, Feng, Jiang, Jie, Zheng, Qingbing, Gao, Shuangquan, Yan, Xiaodong, Li, Shaowei, Gu, Ying, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316451/
https://www.ncbi.nlm.nih.gov/pubmed/30486318
http://dx.doi.org/10.3390/v10120667