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Hepatitis C Virus-Infected Apoptotic Hepatocytes Program Macrophages and Hepatic Stellate Cells for Liver Inflammation and Fibrosis Development: Role of Ethanol as a Second Hit

Hepatocyte apoptosis is a crucially important mechanism for liver disease pathogenesis, and the engulfment of apoptotic bodies (AB) by non-parenchymal cells serves as a leading mechanism of inflammation and fibrosis progression. Previously, we have shown that hepatitis C virus (HCV) and alcohol meta...

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Detalles Bibliográficos
Autores principales: Ganesan, Murali, Poluektova, Larisa Y., Enweluzo, Chijioke, Kharbanda, Kusum K., Osna, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316463/
https://www.ncbi.nlm.nih.gov/pubmed/30322122
http://dx.doi.org/10.3390/biom8040113