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Propranolol Promotes Glucose Dependence and Synergizes with Dichloroacetate for Anti-Cancer Activity in HNSCC

Tumor cell metabolism differs from that of normal cells, conferring tumors with metabolic advantages but affording opportunities for therapeutic intervention. Accordingly, metabolism-targeting therapies have shown promise. However, drugs targeting singular metabolic pathways display limited efficacy...

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Detalles Bibliográficos
Autores principales: Lucido, Christopher T., Miskimins, W. Keith, Vermeer, Paola D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316475/
https://www.ncbi.nlm.nih.gov/pubmed/30513596
http://dx.doi.org/10.3390/cancers10120476