Cargando…
A Gemini Cationic Lipid with Histidine Residues as a Novel Lipid-Based Gene Nanocarrier: A Biophysical and Biochemical Study
This work reports the synthesis of a novel gemini cationic lipid that incorporates two histidine-type head groups (C(3)(C(16)His)(2)). Mixed with a helper lipid 1,2-dioleoyl-sn-glycero-3-phosphatidyl ethanol amine (DOPE), it was used to transfect three different types of plasmid DNA: one encoding th...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316511/ https://www.ncbi.nlm.nih.gov/pubmed/30558369 http://dx.doi.org/10.3390/nano8121061 |