Heteronemin Induces Anti-Proliferation in Cholangiocarcinoma Cells via Inhibiting TGF-β Pathway

A marine sesterterpenoid-type natural product, heteronemin, retains anticancer effects. In the current study, we investigate the antitumor mechanism of heteronemin in cholangiocarcinoma cells and further explore its molecular targets. Initially, heteronemin exhibited potent cytotoxic effects against...

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Detalles Bibliográficos
Autores principales: Lin, Hung-Yun, Tey, Shu-Leei, Ho, Yih, Chin, Yung-Tang, Wang, Kuan, Whang-Peng, Jacqueline, Shih, Ya-Jung, Chen, Yi-Ru, Yang, Yung-Ning, Chen, Yu-Cheng, Liu, Yi-Chang, Tang, Heng-Yuan, Yang, Yu-Chen SH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316595/
https://www.ncbi.nlm.nih.gov/pubmed/30563284
http://dx.doi.org/10.3390/md16120489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316595/
https://www.ncbi.nlm.nih.gov/pubmed/30563284
http://dx.doi.org/10.3390/md16120489

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