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Heteronemin Induces Anti-Proliferation in Cholangiocarcinoma Cells via Inhibiting TGF-β Pathway
A marine sesterterpenoid-type natural product, heteronemin, retains anticancer effects. In the current study, we investigate the antitumor mechanism of heteronemin in cholangiocarcinoma cells and further explore its molecular targets. Initially, heteronemin exhibited potent cytotoxic effects against...
Autores principales: | Lin, Hung-Yun, Tey, Shu-Leei, Ho, Yih, Chin, Yung-Tang, Wang, Kuan, Whang-Peng, Jacqueline, Shih, Ya-Jung, Chen, Yi-Ru, Yang, Yung-Ning, Chen, Yu-Cheng, Liu, Yi-Chang, Tang, Heng-Yuan, Yang, Yu-Chen SH |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316595/ https://www.ncbi.nlm.nih.gov/pubmed/30563284 http://dx.doi.org/10.3390/md16120489 |
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