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Structural Features and Binding Modes of Thioether-Cyclized Peptide Ligands

Macrocyclic peptides are an emerging class of bioactive compounds for therapeutic use. In part, this is because they are capable of high potency and excellent target affinity and selectivity. Over the last decade, several biochemical techniques have been developed for the identification of bioactive...

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Detalles Bibliográficos
Autores principales: Otero-Ramirez, Manuel E., Passioura, Toby, Suga, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316662/
https://www.ncbi.nlm.nih.gov/pubmed/30551606
http://dx.doi.org/10.3390/biomedicines6040116